Insoluble saccharinThe carcinogenic suspicion has already dissipated.
Insoluble saccharinIt is a synthetic sweetener, and its sweetness can reach sucrose.500 times times.
InIn 1977, a study reported that when rats fed a large dose of insoluble saccharin (roughly the amount of saccharin contained in hundreds of cans of cola), they sufferBladder cancerThe probability of a significant increase. In this year,CanadaThe use of saccharin is prohibited, whileU.S. Food and Drug AdministrationA ban was put forward prohibiting the use of saccharin in food. At that time, Saccharin was the only one in the U.S. market.Substituting sugar, the ban has aroused strong opposition from the people, especiallyDiabetesPatients. At lastUnited States CongressSuspend the saccharin ban, stipulating that all foods containing saccharin must display a warning label indicating that' saccharin may be a carcinogenic substance in mice '.
Some studies have shown that theAnimal experimentsThe possibility of causing bladder cancer was found in animalsCarcinomaFor positive, a large intake can causePlateletReduce and cause acute haemorrhage, can damageCellsStructure andLiver、Renal, will induceBladder cancer。 However, no adverse effects were found in human trials.
Many studies have confirmed the insoluble saccharin with the sufferingCancerThere is no correlation between (especially bladder cancer). All studies point to a clear fact that the normal dosage of saccharin consumption does not have much impact on human health. Doubts about the safety of insoluble saccharin and anhydrous saccharin sodium have come from a flawed study, which points to a large number of sugar-free laboratory whiteMouseThe adverse effects of bladder tumors. Further studies show that the carcinogenic principle of saccharin in microscope does not apply to humans. National Institute of Environmental Health Sciences, USAThe same conclusion was reached in 2000 that Saccharin had been removed from the list of suspected carcinogens.
InIn 1991, 14 years after the ban was released, the FDA formally withdrew its proposal to disable saccharin, and in 2000, Congress abolished the regulations, and insoluble saccharin products did not have to be labelled with health warnings.
Mainland China allowed to useInsoluble saccharin, but with limited dosage:Foodshould be less than0.150G/KG,Salt sodashould be less than0.08g/kg.